Exercício físico reduz a dor muscular inflamatória induzida por carragenina

Abstract

Muscle pain can be inflammatory and affects a large part of the world population. One strategy for reducing pain and inflammation is to perform physical exercise. To demonstrate the effect of physical exercise on carrageenan- induced inflammatory muscle pain. Method: Thirty male mice were divided into groups: Control that received only i.m saline; Carrageenan which received 20 ul of carrageenan i.m; and Carrageenan + Exercise, which was treated with 30min treadmill at 10m / min five week days for 2 weeks. The animals were evaluated for mechanical and thermal hypersensitivity, edema and escape / avoidance paradigm. The physical exercise group presented reduction of hyperalgesia. Although carrageenan induced the onset of muscle edema, exercise did not modify it. No difference was observed in the fugue / avoidance paradigm in the experimental groups. Exercise was able to reduce carrageenin-induced hyperalgesia, but was not able to reduce muscle edema.