Efeito protetor do gama orizanol sobre as alterações comportamentais e bioquímicas induzidas pela exposição aguda da mosca da fruta Drosophila melanogaster ao estresse térmico

Abstract

Evaluate the protector effect of gamma oryzanol in the biochemical and behavior alterations of the fruit fly Drosophila melanogaster when exposed to thermal stress. The flies were divided in groups according to the treatment, where they were exposed to the cold to induce stress and gamma oryzanol as a treatment way. Compartmental tests such as Negative geotaxis, Base Top and Open field were utilized to test the flies locomotor activity. However, the biochemical analysis ex vivo, were realized, such as: stress level relative measure and TBARS and enzymes superoxide dismutase, catalase, acetylcholinesterase activity and evaluation of cellular viability using resaruzin method. The flies exposed to the thermal stress had the locomotor activity affected, they also had the biochemical alterations, by the way, the flies were treated with the gamma oryzanol compound, however, exposed in the same stress conditions, they do not obtained any alteration about the control group.The gamma oryzanol compound was able to protect the fruit fly Drosophila melanogaster to the behavior and biochemical damage caused by thermal stress exposition.