Mensuração do lactato sanguíneo e peritoneal como auxiliar diagnóstico e prognóstico em equinos com síndrome cólica

Abstract

Colic syndrome due to gastrointestinal causes constitutes the largest proportion of equine emergency care in referral hospitals. The study of fast and sensitive ways for the early identification of equine diseases, which occur with acute abdomen, are fundamental for the reduction of mortality, economic losses and diagnostic reliability. Lactate is the product of glycolysis under anaerobic conditions, and its increase may indicate intestinal disorders with tissue hypoperfusion and hypoxia. The objective of this study was to verify if the values of blood and peritoneal lactate, at the admission of horses with colic syndrome, are related to the type of condition, therapeutic referral and survival. A retrospective analysis of consultations with colic syndrome between 2016 and 2020 was used at the EQUIVET Veterinary Hospital, located in Indaiatuba- São Paulo, Brazil. Out of the 498 verified records of consultations with colic syndrome, 89 cases were selected by the inclusion criteria. Logistic regression analysis indicated that peritoneal lactate was more significant compared to blood in the variables related to the type of obstruction and survival during admission. Strangulation changes were observed in 26% of the cases, 52.8% of the consultations required surgery and had an overall survival rate of 62.9%. In strangulating alterations, the average blood lactate was 5.11 mmol/L and peritoneal 7.33 mmol/L, while in simple processes 3.54 mmol/L for the blood and 3.06 mmol/L for the peritoneal. The average blood and peritoneal lactate was 3.43mmol/L and 2.42mmol/L of the survivors, respectively, and in non-survivors the average was 4.84 and 7.13 mmol/L. However, therapeutic referral was not statistically significant with the measurement of lactate at admission. It can be concluded that the measurement of peritoneal lactate at the admission of horses with colic syndrome was considered a predictor of the type of condition, as well as the survival and prognosis of these patients. On the other hand, the evaluation of blood and peritoneal lactate measurements did not help in the decision of therapeutic referral.